Pain – We have extensive experience with all aspects of analgesic development (Phase 1 through Phase 4) and have worked with both opioids and non-opioids, biologics and small molecules, NCEs and novel formulations of established analgesics.  We have designed and conducted dozens of studies focused on all types of acute pain, chronic pain, post-op pain, nociceptive pain, neuropathic pain, headaches, and other varieties of pain.

Peripheral Neuropathy – In addition to neuropathic pain, we have designed and conducted studies targeting various types of peripheral neuropathy, both large fiber and small fiber neuropathies, focal and non-focal.  We have particular extensive experience working with diabetic neuropathy.

CNS Disorders – We have designed and conducted studies focused on the treatment of Parkinson’s disease, Alzheimer’s disease, epilepsy, stroke, multiple sclerosis, depression, schizophrenia, and anxiety.

Metabolic disorders – We have experience conducting studies focused on the treatment of diabetes mellitus, cachexia related to cancer, pulmonary disease and congestive heart failure.  In addition, we have designed trials for the treatment of hyponatremia and pruritis.

Autoimmune Disorders - We have participated in studies of antibodies targeting T-cell antigens related to a variety of autoimmune disorders including:  type 1 diabetes, cutaneous lupus and psoriasis.

Cancer - We have experience designing early stage trials for the treatment of ovarian carcinoma, neurofibromatosis type I and type II, and have participated in the design and conduct of studies of cancer complications including cancer related pain and cachexia.

Vaccine – We have participated in early phase studies of a vaccine for West Nile Virus.